Second tumours after breast cancer: Is it still too soon to tell?

Multiplicities in the assessment of multiple vitamins: is it too soon to tell men that vitamins prevent cancer?

IN THIS ISSUE OF JAMA, GAZIANO AND COLLEAGUES 1 REport one of several analyses of data from the Physicians’ Health Study II (PHS II) randomized controlled trial. Among more than 14 000 male physicians who participated in this study, the authors report a marginally statistically significant (P=.04) inverse relationship between taking a daily multivitamin (Centrum Silver) and the occurrence of ca...

Is it too soon to start reporting HER2 genetic heterogeneity?

No wonder you activities are, reading will be always needed. It is not only to fulfil the duties that you need to finish in deadline time. Reading will encourage your mind and thoughts. Of course, reading will greatly develop your experiences about everything. Reading is it too soon to start reporting her2 genetic heterogeneity letters the editor letter is also a way as one of the collective bo...

No heroic measures: how soon is too soon to stop?

It's too soon to know.

As I read the paper "Sector Resection With or Without Postoperative Radiotherapy for Stage I Breast Cancer: A Randomized Trial," by Holmberg and colleagues (/), I found myself distressed that it had been accepted for publication, since I believe that it is premature to make the interpretations for which the study was designed and that the authors make. While not changing my view on premature in...

Don't cut too soon

JCB • VOLUME 173 • NUMBER 3 • 2006 316 C aren Norden, Manuel Mendoza, Yves Barral (ETH, Zurich, Switzerland), and colleagues have found a new checkpoint in yeast cell division. Cytokinesis, they show, is delayed until chromosomes are out of the way, thanks to a pathway that monitors the spindle midzone. If cytokinesis were to occur too soon, chromatids still lingering in the spindle midzone mig...